To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography.
LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients.
A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1).
Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.
1Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana, USA;
2Department of Biostatistics, Indiana University-Purdue University, Indianapolis, Indiana, USA.
Correspondence: Naga Chalasani, MD. E-mail: email@example.com.
Received October 17, 2018
Accepted December 11, 2018