1BioTechnology Institute, University of Minnesota, St Paul, MN, USA
2Division of Gastroenterology, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
3Center for Immunology, University of Minnesota, MN, USA
Correspondence: Michael J. Sadowsky, PhD, University of Minnesota, Professor of Medicine, 2101 6th Street S.E.; Room 3-184, Wallin Biomedical Sciences Building, Minneapolis, MN 55414, USA[email protected]
Correspondence: Michael J. Sadowsky, PhD, McKnight University Professor, University of Minnesota, BioTechnology Institute, 1479 Gortner Avenue, 140 Gortner Labs, St. Paul, MN 55108, USA. E-mail: [email protected]
4Shares first authorship.
5Shares senior authorship
SUPPLEMENTARY MATERIAL accompanies this paper at https://links.lww.com/AJG/A475
Received 02 July 2016; accepted 02 December 2016
Guarantor of the article: Alexander Khoruts, MD.
Specific author contributions: Christopher Staley: analysis and interpretation of data; critical revision of the manuscript for intellectual content; statistical analysis. Matthew J. Hamilton: acquisition of data; analysis and interpretation of data; critical revision of the manuscript for intellectual content. Byron P. Vaughn: acquisition of data; critical revision of the manuscript for intellectual content. Carolyn T. Graiziger: acquisition of data; technical support. Krista M. Newman: acquisition of data. Amanda J. Kabage: administrative and technical support. Michael J. Sadowsky: study concept and design; analysis and interpretation of data; critical revision of the manuscript for intellectual content; obtained funding; study supervision. Alexander Khoruts: study concept and design; acquisition of data; analysis and interpretation of data; drafting the manuscript; obtained funding; study supervision.
Financial support: The study was supported by grants from the NIH 1R21-AI114722-01 (AK, MJS) to analyze the bacterial composition of the fecal samples, CIPAC Limited (AK, MJS) to test various parameters for optimization of microbiota preparation. Additional support for capsule preparation and collection biological specimens was provided by the philanthropic support of Achieving Cures Together, Ms. Emily Haller, and the Hubbard Foundation. None of the sponsors had any roles (other than funding) in the study design, collection, analysis, interpretation of data, or writing of the manuscript.
Potential competing interests: AK and MJS received research grant support from CIPAC Limited. MJH, AJK, and MJS provided consulting services to CIPAC Limited and Crestovo LLC. AK serves on the advisory board for Merck. BPV receives research salary support from Roche and speaking consulting fees from Janssen and Abbvie. The remaining authors declare no conflict of interest.
