1University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
2North Mississippi Medical Center, Tupelo, Mississippi, USA
3University of Michigan, Ann Arbor, Michigan, USA
4Indiana University, Indianapolis, Indiana, USA
5Ohio State University, Columbus, Ohio, USA
6Medical University of South Carolina, Charleston, South Carolina, USA
7Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
8Mayo Clinic, Jacksonville, Florida, USA
9Saint Louis University, St Louis, Missouri, USA
10Richmond Gastroenterology Associates, Richmond, Virginia, USA
11Aurora Health Care, Milwaukee, Wisconsin, USA
12Yale School of Medicine, New Haven, Cincinnati, USA
13Virginia Commonwealth University, Richmond, Virginia, USA
14Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
15University of Chicago, Chicago, Illinois, USA
16University of Florida, Gainesville, Florida, USA
17Brigham and Women’s Hospital, Boston, Massachusetts, USA
18University of Alabama at Birmingham, Birmingham, Alabama, USA
Correspondence: Dhiraj Yadav, MD, MPH, Division of Gastroenterology & Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, 200 Lothrop Street, M2, C-wing, Pittsburgh, Pennsylvania 15213, USA. E-mail: [email protected]
Received 02 October 2016; accepted 09 January 2017
Guarantor of the article: Dhiraj Yadav, MD, MPH.
Specific author contributions: Study design: Jorge D. Machicado, Judah N. Abberbock, and Dhiraj Yadav. Data acquisition: C. Mel Wilcox, Bimaljit S. Sandhu, Vikesh K. Singh, Andres Gelrud, Stuart Sherman, Gregory A. Cote, Samer Al-Kaade, Michelle A. Anderson, Timothy B. Gardner, Michele D. Lewis, Christopher E. Forsmark, Nalini M. Guda, Joseph Romagnuolo, John Baillie, Stephen T. Amann, Thiruvengadam Muniraj, Darwin L. Conwell, Peter A. Banks, Randall E. Brand, Adam Slivka, and Dhiraj Yadav. Statistical analysis: Judah N. Abberbock and Gong Tang. Drafting of the manuscript: Jorge D. Machicado and Dhiraj Yadav. Data interpretation, review of manuscript for important intellectual content, final approval of the manuscript: all authors.
Financial support: The study was supported by R01DK061451 (D.C.W.), R01 DK077906 (D.Y.), UO1 DK108306 (D.C.W., D.Y.), U01 DK 108320 (C.E.F.), U01 DK 108327 (D.C.), and UL1 RR024153 and UL1TR000005 (PI—Steven E. Reis, MD).
Potential competing interests: Dr Whitcomb is an inventor of intellectual property that is licensed to Ambry Genetics, which has been evaluated in this study. He also has an ownership interest in Ambry Genetics. The other authors declare no conflict of interest.
