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Primary amyloidosis of the mesentery and the retroperitoneum presenting with lymphedema

Halm, Ulrich, MD1,*; Berr, Frieder, MD1; Tannapfel, Andrea, MD2; Klöppel, Rainer, MD3; Secknus, Roger, MD1; Mössner, Joachim, MD1

American Journal of Gastroenterology: November 1998 - Volume 93 - Issue 11 - p 2299–2300
doi: 10.1111/j.1572-0241.1998.00647.x
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We report the case of a 57-yr-old woman presenting with moderate weight loss, abdominal distension, and lymphedema of the legs and vulva. Computed tomography of the abdomen revealed massive thickening of the rectal wall, mesentery, and retroperitoneum. Primary amyloidosis was diagnosed by immunohistochemistry from the rectum and duodenum. To our knowledge, lymphedema due to primary amyloidosis has not yet been reported. The diagnosis should be presumed in the case of retroperitoneal thickening and lymphedema and can be established by immunohistochemistry.

1Department of Internal Medicine II, University of Leipzig, Leipzig, Germany

2Institute of Pathology, University of Leipzig, Leipzig, Germany

3Department of Diagnostic Radiology, University of Leipzig, Leipzig, Germany

*Department of Internal Medicine II, University of Leipzig, Philipp-Rosenthal-Strasse 27, D-04103 Leipzig, Germany

© The American College of Gastroenterology 1998. All Rights Reserved.
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