Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

LIVER FAILURE CAUSED BY HEPATIC ANGIODYSPLASIA IN HEREDITARY HEMORRHAGIC TELANGIECTASIA

Mukasa, Chizu, MD; Nakamura, Kazuhiko, MD*; Chijiiwa, Yoshihara, MD; Sakai, Hironori, MD; Nawata, Hajime, MD

American Journal of Gastroenterology: March 1998 - Volume 93 - Issue 3 - p 471–473
doi: 10.1111/j.1572-0241.1998.468_3.x
BRIEF CASE REPORTS: PDF Only
Buy

Hereditary hemorrhagic telangiectasia is a systemic vascular disease with autosomal dominant inheritance that results in telangiectasia, arteriovenous malformations, and hemangiomas. The liver is one of the organs commonly affected in hereditary hemorrhagic telangiectasia, and hepatic lesions consist of angiodysplasia and fibrosis. A patient with hereditary hemorrhagic telangiectasia and significant impairment of synthetic liver function is reported. Dynamic computed tomography revealed marked enlargement of the common hepatic and intrahepatic arteries, heterogeneous parenchymography, and early opacification of the hepatic veins consistent with telangiectasias and arteriovenous shunting. Overall, the liver was predominantly occupied by vascular structures and scarce residual hepatic parenchyma. Other causes of liver dysfunction, such as viral hepatitis and alcohol abuse, were excluded. In general, hepatic fibrovascular dysplasia seen in hereditary hemorrhagic telangiectasia usually results in only mild liver dysfunction; however, this case shows that hepatic involvement may rarely result in hepatic failure.

The Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan

*The Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-82, Japan.

© The American College of Gastroenterology 1998. All Rights Reserved.
You currently do not have access to this article

To access this article:

Note: If your society membership provides full-access, you may need to login on your society website