Several areas of broad agreement exist concerning the management of specific patient groups with clear-cut complications of H. pylori-colonization. Other aspects of this infection remain less well defined. These include the mode of transmission and pathogenesis of H. pylori, the clinical management of patients who do not have ulcer disease, and the approach to populations at risk of the clinical consequences of this bacterium. This review focuses on the unresolved issues of H. pylori infection that are of concern to the clinical gastroenterologist.
Department of Medicine, St. Luke's/Roosevelt Hospital Center, New York, New York; Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan; Department of Medicine, St. Elizabeth's Medical Center, Boston, Massachusetts; and Department of Surgery, Yale University School of Medicine, New Haven, Connecticut
*Yale University School of Medicine, Department of Surgery, Box 208062, New Haven, CT 06520-8062.