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Polypharmacy and evaluation of anticholinergic risk in a cohort of elderly people living with HIV

Mazzitelli, Mariaa,b; Milinkovic, Anab; Pereira, Brancab; Palmer, Jamesc; Tong, Timothyb; Asboe, Davidb; Boffito, Martab,c

doi: 10.1097/QAD.0000000000002403
Research Letter
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As a consequence of ageing, the number of prescribed medications for people living with HIV is increasing. Concomitant use of different drugs and their potential interactions may increase anticholinergic exposure and escalate the risk for side effects. We conducted an analysis in our cohort of people living with HIV over 50 years of age to evaluate the overall anticholinergic risk, as it is useful to identify, prevent, and manage increased side effect risks.

a‘Magna Graecia University’, Catanzaro, Italy

bChelsea and Westminster Hospital NHS Foundation Trust

cImperial College London, London, UK.

Correspondence to Dr Maria Mazzitelli, MD, Magna Graecia University, Catanzaro, Italy; Chelsea and Westminster Hospital, London, UK. E-mail: m.mazzitelli88@gmail.com

Received 26 July, 2019

Revised 22 August, 2019

Accepted 2 September, 2019

Copyright © 2019 Wolters Kluwer Health, Inc.