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Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

Morgan, Ethan; Taylor, Harry E.; Ryan, Daniel Timothy; D’Aquila, Richard; Mustanski, Brian

doi: 10.1097/QAD.0000000000002093
Research Letters

Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.

Northwestern University, Chicago, IL, USA.

Correspondence to Brian Mustanski, PhD, 625 N Michigan Ave, Suite 14-061, Chicago, IL 60611, USA. E-mail:

Received 16 August, 2018

Accepted 6 November, 2018

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