Original paper: PDF OnlyClinical experience of AIDS in relation to HIV-1 and HIV-2 infection in a rural hospital in Ivory Coast, West AfricaGody, Michel; Ouattara, Soungalo A.*; de Thé, Guy† Author Information From the Medicus Mundi, Belgium, Protestant Hospital, Dabou, Ivory Coast, *Pasteur Institute, Abidjan, Ivory Coast, †CNRS Laboratory of Epidemiology and Immunovirology of Tumors, Faculty of Medicine Alexis Carrel, Lyon, France and, †Department of Cancer Biology, Harvard School of Public Health, Boston, MA, USA. AIDS: December 1988 - Volume 2 - Issue 6 - p 433-436 Buy Abstract A dramatic rise in AIDS cases in a rural hospital 60 km west of Abidjan is described. Out of 212 adult cases diagnosed between January and November 1987 as having AIDS, using the World Health Organization (WHO) criteria defined in Bangui , 128 (60%) had antibodies to HIV-1 only, 61 (29%) had antibodies to both HIV-1 and HIV-2, 15 (7%) had antibodies to HIV-2 only and eight (4%) had no detectable antibodies to HIVs. These results, taken together with those of Ouattara et al.  showing that both retroviruses have a similar seroprevalence in the general rural and urban populations, suggest that HIV-2 may have a lower physiopathological potential than HIV-1. This suggestion is supported by a 6-month follow-up of 60 AIDS cases, but only longer follow-up of cohorts of patients and healthy subjects with antibodies to one of the two viruses will allow definitive conclusions. © Lippincott-Raven Publishers.