1Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component-based Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
2Second Affiliated hospital of Tianjin University of Traditional Chinese Medicine, 69 Zengchan Road, Hebei District, Tianjin 300250, China.
Yanchao Xing, Xiaoming Wang and Xianrui Wang contributed equally to this work.
Funding This work was supported by the National Natural Science Foundation of China (grant no. 81303182, 81173523) and the National Major Scientific and Technological Special Project for “Significant New Drugs Development” (Grants No.2018ZX09734-002).
Ethical Approval of Studies and Informed Consent The study followed the guidelines of the ethics committee of the Experimental Animal Center of Tianjin University of Traditional Chinese Medicine (ethical registration number: 20160712-02).
Acknowledgments None.
Supplemental Digital Content: The supplemental digital content can available online.
*Correspondence author. Lifeng Han, Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component-based Chinese Medicine, No.10 Poyanghu Road, Jinghai District, Tianjin 301617, China, [email protected].
*Correspondence author. Guixiang Pan. Second Affiliated hospital of Tianjin University of Traditional Chinese Medicine, 69 Zengchan Road, Hebei District, Tianjin 300250, China, [email protected].
Conflicts of Interest statement: None
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