CASES OF NOTECaution Ahead Identifying Red Flag Signs and Symptoms in Patients With MigraineCook, Calli DNP, APRN, FNP-C, FAANPEditor(s): Jordan, Kathleen S. DNP, RN, FNP-BC, ENP-C, SANE-P, FAEN, FAANP, Column Editor Author Information Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, and Emory Brain Health Center, Atlanta, Georgia. Corresponding Author: Calli Cook, DNP, APRN, FNP-C, FAANP, Emory Brain Health Center, 12 Executive Park Dr NE, Atlanta, GA 30329 ([email protected]). Disclosure: The author reports no conflicts of interest. Advanced Emergency Nursing Journal: October/December 2022 - Volume 44 - Issue 4 - p 281-284 doi: 10.1097/TME.0000000000000430 Buy Metrics Abstract Headache is a commonly encountered symptom in urgent care and the emergency department. Headache syndromes are classified a primary headache and do not require neuroimaging; however, patients should be assessed at each encounter for changes in their headache symptoms. This case highlights a patient who was suffering from a new headache type, characterized as different from her previous attacks and unyielding to her current acute and preventive treatment methods. The patient was sent for neuroimaging and found to have a mass within her sella turcica that required surgical intervention and removal. Assessing headache patients for red flag symptoms can uncover significant alterations in the patient's symptomatology and indicate a need for further evaluation. By evaluating for red flag symptoms, clinicians can ensure the delivery of high-quality care and better health care outcomes for patients with headache disease. © 2022 Wolters Kluwer Health, Inc. All rights reserved.