DERMATOLOGY DILEMMASRecognizing Recurrence of Melanoma in an Emergency Department Patient A Case StudyCulbertson, Amy DNP, APRN, FNP-BC; Huey, Sally DNP, APRN, FNP-BCEditor(s): Martinez, Nicole PhD, APRN, FNP-BC, ENP-C, PHN, Column Editor Author Information Georgetown University School of Nursing and Health Studies, Washington, District of Columbia. Corresponding Author: Amy Culbertson, DNP, APRN, FNP-BC, Georgetown University School of Nursing and Health Studies, 3700 Reservoir Rd NW, Washington, DC 20057 ([email protected]). Disclosure: The authors report no conflicts of interest. Advanced Emergency Nursing Journal: April/June 2022 - Volume 44 - Issue 2 - p 109-115 doi: 10.1097/TME.0000000000000402 Buy Metrics Abstract Malignant melanoma incidence is rising faster than any other malignancy. Recurrent disease can occur in as many as 10% of patients diagnosed with primary malignant melanoma. In-transit melanoma is a type of locoregional disease that materializes when the cancer recurs as dermal and subdermal nodules found between the primary site and the lymph node drainage basin. Patients may not recognize the lesions as in-transit melanoma, and they may present to the emergency department for another matter completely. Ultimately, once recurrence is suspected, there must be a swift referral to oncology. Lack of recognition of this unique skin lesion could prove to be fatal. As frontline providers of care, emergency nurse practitioners should be alert to the characteristics of these lesions and the history that supports this dermatological condition. © 2022 Wolters Kluwer Health, Inc. All rights reserved.