ECG CASES COLUMNElectrocardiographic Findings Associated With Neurological Pathology and Other T-Wave CatastrophesDavis, Wesley D. DNP, ENP-C, FNP-C, AGACNP-BC, CEN; Goettl, Bradley DNP, ENP-C, FNP-C, AGACNP-BC, EMT-P; Bowden, Leah BSN, RNEditor(s): Davis, Wesley D. DNP, ENP-C, FNP-C, AGACNP-BC, CEN, Column Editor Author Information College of Nursing, University of South Alabama, Mobile (Dr Davis); Department of Emergency Medicine, UT Health San Antonio, San Antonio, Texas (Dr Goettl); and Emergency Department, Piedmont Columbus Regional Hospital, Columbus, Georgia (Ms Bowden). Corresponding Author: Wesley D. Davis, DNP, ENP-C, FNP-C, AGACNP-BC, CEN, College of Nursing, University of South Alabama, 5721 USA Dr, North, Mobile, AL 36688 ([email protected]). Disclosure: The authors report no conflicts of interest. Advanced Emergency Nursing Journal: July/September 2021 - Volume 43 - Issue 3 - p 212-216 doi: 10.1097/TME.0000000000000357 Buy Metrics Abstract An 87-year-old female patient presented with altered mental status. During the routine workup for altered mental status, an electrocardiogram (ECG) was obtained. The ECG showed T-wave morphology known to be consistent with myocardial infarction. Although the ECG is a crucial diagnostic tool to recognize myocardial ischemia and infarction promptly, it must be understood that T-wave abnormalities can represent noncardiac pathology. A case presentation illustrates a unique ECG change whose presence is associated with catastrophic central nervous system diseases that cause increased intracranial pressure. © 2021 Wolters Kluwer Health, Inc. All rights reserved.