APPLIED PHARMACOLOGYA Review on the Reversal of the Old and New AnticoagulantsBailey, Abby Mynatt PharmD, BCPS; Blackburn, Matthew C. PharmD, BCPS; Crowley, John M. PharmD, BCPS; Horn, Kari S. PharmD; Schultz, Amy E. PharmD; Justice, Stephanie Baker PharmD, BCPSSection Editor(s): Weant, Kyle A. PharmD, BCPS; Column Editor Author Information University of Kentucky HealthCare, Lexington (Drs Bailey, Blackburn, and Horn); University of Kentucky College of Pharmacy, Lexington (Dr Bailey); Charleston Area Medical Center, Charleston, West Virginia (Drs Crowley and Schultz); University of Charleston School of Pharmacy, Charleston, West Virginia (Drs Crowley and Schultz); West Virginia University School of Pharmacy, Morgantown (Drs Crowley and Schultz); and St. Claire Regional Medical Center, Morehead, Kentucky (Dr Justice). Corresponding Author: Stephanie Baker Justice, PharmD, BCPS, St. Claire Regional Medical Center, 222 Medical Circle, Morehead, KY 40351 (firstname.lastname@example.org). Disclosure: The authors report no conflicts of interest. Advanced Emergency Nursing Journal: October/December 2016 - Volume 38 - Issue 4 - p 279-294 doi: 10.1097/TME.0000000000000123 Buy Take the CE Test Metrics Abstract It is not uncommon for providers in the emergency department to take care of patients who are taking anticoagulant therapy in the outpatient setting. However, the bigger challenge is caring for these patients when they present with bleeding that could be secondary to 1 or more of these medications. In recent years, this class of medications has expanded from warfarin to include direct thrombin inhibitors and Factor Xa inhibitors. As this class of medications has evolved, so has the approach to the reversal of these agents. Thus, it is imperative that providers in the emergency department be familiar not only with the anticoagulants that patients may be taking in the outpatient setting but also with their reversal agents. © 2016 Wolters Kluwer Health, Inc. All rights reserved.