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Adverse effects of laxatives: updateCorrespondence

Anton, Christopher; Crawford, Colin

doi: 10.1097/FAD.0000000000000023
Invited Review Article

Summary Laxatives are generally well tolerated and adverse effects mild or moderate, although rarely adverse effects can be fatal. Several laxatives have recently been licensed for intractable constipation not relieved by simple laxatives, opioid-induced constipation, and irritable bowel syndrome with constipation. Like the older laxatives, the new laxatives usually cause only mild adverse effects, although some serious effects have been reported.

West Midlands Centre for Adverse Drug Reactions, City Hospital, Birmingham, UK

Retired physician

Correspondence to Mr Christopher Anton, West Midlands Centre for Adverse Drug Reactions, City Hospital, Birmingham, UK. E-mail:

Correspondence to Dr Colin Crawford, 17 Gloucester Court, 516 Lordship Lane, East Dulwich, London SE22 8GB, UK. E-mail:

Editor: R E Ferner, MSc, MD, FRCP, Director of the West Midlands Centre for Adverse Drug Reaction Reporting and Consultant Physician at City Hospital, Birmingham, UK. Assistant Editor: Mr C Anton, MA, MEng. Editorial Board: Australia: Dr M Kennedy, Professor G M Shenfield, Denmark: Professor J S Schou; England: Dr J K Aronson, Dr A Hitchings; India: Professor N Gogtay; Netherlands: Professor C J van Boxtel, Dr B H Ch Stricker; New Zealand: Dr T Maling; Scotland: Dr D N Bateman; Wales: Professor P A Routledge.

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