Secondary Logo

Institutional members access full text with Ovid®

Share this article on:

Drugs that lower the seizure threshold

Hitchings, Andrew W.

Adverse Drug Reaction Bulletin: June 2016 - Volume 298 - Issue 1 - p 1151–1154
doi: 10.1097/FAD.0000000000000016
Invited Review Article

Summary Drugs with potential to lower the seizure threshold are numerous and diverse. Whether they contribute to clinically overt seizures depends on the dosage in which they are taken, the time-course of their effects and the susceptibility of the patient. Crucially, however, their contribution to seizure risk is potentially modifiable.

Departments of Clinical Pharmacology and Neuro-Intensive Care, St George's, University of London and St George's University Hospitals NHS Foundation Trust, Cranmer Terrace, London, SW17 0RE, UK

Correspondence to Andrew W. Hitchings, Senior Lecturer in Clinical Pharmacology and Honorary Consultant in Neuro-Intensive Care, St George's, University of London and St George's University Hospitals NHS Foundation Trust Cranmer Terrace, London SW17 0RE, UK. E-mail: ahitchin@sgul.ac.uk

Editor: R E Ferner, MSc, MD, FRCP, Director of the West Midlands Centre for Adverse Drug Reaction Reporting and Consultant Physician at City Hospital, Birmingham, UK. Assistant Editor: Mr C Anton, MA, MEng. Editorial Board: Australia: Dr M Kennedy, Professor G M Shenfield, Denmark: Professor J S Schou; England: Dr J K Aronson; India: Professor N Gogtay; Netherlands: Professor C J van Boxtel, Dr B H Ch Stricker; New Zealand: Dr T Maling; Scotland: Dr D N Bateman; Wales: Professor P A Routledge.

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.