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Adverse effects of anticoagulants

Veiraiah, Aravindan; Routledge, Philip Alexander

Adverse Drug Reaction Bulletin: October 2009 - Volume - Issue 258 - p 991–994
doi: 10.1097/FAD.0b013e3283336628
Original Article

All anticoagulant treatment increases the risk of bleeding. Warfarin causes foetal abnormalities – chrondrodysplasia punctata, and asplenia – and may increase foetal loss rate; skin necrosis and rarer adverse reactions. Unfractionated heparins can cause osteoporosis, thrombocytopenia with or without thrombosis, and other rare reactions. Low molecular weight heparins are less likely to do so.

Section of Pharmacology, Therapeutics and Toxicology, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN

Editor: R E Ferner, MSc, MD, FRCP, Director of the West Midlands Centre for Adverse Drug Reaction Reporting and Consultant Physician at City Hospital, Birmingham, UK. Assistant Editor: Mr C Anton, MA, MEng. Editorial Board: Australia: Dr M Kennedy, Professor G M Shenfield, Denmark: Professor J S Schou; England: Dr J K Aronson; Ireland: Professor J Feely; Netherlands: Professor C J van Boxtel, Dr B H Ch Stricker; New Zealand: Dr T Maling; Scotland: Dr D N Bateman; Wales: Professor P A Routledge.

© 2009 Lippincott Williams & Wilkins, Inc.