Original ArticlesFrailty in the Context of Older People Living With HIV A Concept AnalysisIriarte, Evelyn MSN, BSN, RN; Cianelli, Rosina PhD, MPH, RN, IBCLC, FAAN; De Santis, Joseph PhD, APRN, ACRN, FAANAuthor Information School of Nursing and Health Studies, University of Miami, Coral Gables, Florida (Ms Iriarte and Drs Cianelli and De Santis); and School of Nursing, Pontificia Universidad Catolica de Chile, Santiago, Chile (Ms Iriarte and Dr Cianelli). Correspondence: Evelyn Iriarte, MSN, BSN, RN, School of Nursing, University of Miami, Schwartz Center for Nursing and Health Studies, 5030 Brunson Dr, Coral Gables, FL 33146 ([email protected]). This work was funded by the National Agency for Research and Development (ANID)/Scholarship Program/DOCTORADO BECAS CHILE/2019-72200262. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Advances in Nursing Science: October/December 2021 - Volume 44 - Issue 4 - p 340-356 doi: 10.1097/ANS.0000000000000384 Buy Metrics Abstract Despite advances in knowledge about older people living with HIV infection (PLWH), frailty remains a challenge to HIV care. Numerous studies have documented its impact; however, the concept remains unclear. Concept exploration of frailty in the context of older PLWH was conducted to provide a comprehensive understanding of the concept based on the Walker and Avant method. After the literature review, a concept analysis and a definition of frailty among older PLWH emerged. Implications for further practice, education, public policy, and research are presented to use the concept consistently, develop interventions to prevent frailty, and improve health outcomes. © 2021 Wolters Kluwer Health, Inc. All rights reserved.