Original articlesExistential Contradictions in Living With End-Stage Renal Disease A Qualitative MetasynthesisKristensen, Ingrid Villadsen MScN; Henriksen, Jette PhD, MScN; Birkelund, Regner PhD, Dr Phil, MScN; Norlyk, Annelise PhD, MScNAuthor Information Section for Nursing, Department of Public Health, Aarhus University, Aarhus, Denmark (Ms Kristensen and Dr Norlyk); VIA Faculty of Health Sciences, VIA Nursing, Holstebro, Denmark (Ms Kristensen); VIA Nursing, VIA University College, Aarhus, Denmark (Dr Henriksen); and Lillebaelt Hospital, Vejle & Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark (Dr Birkelund). Correspondence: Ingrid Villadsen Kristensen, MScN, Section for Nursing, Department of Public Health, Aarhus University, Gl Struervej 1, 7500 Holstebro, Denmark (email@example.com). The authors acknowledge librarian Mai Aggerbeck, who supported the literature search persistently. All authors contributed to the study design and contributed to the manuscript preparation. This work was supported by VIA Faculty of Health Sciences, Via University College; Department of Public Health, Aarhus University and the Kidney Organization in Denmark. The authors declare that they have no conflict of interests. Advances in Nursing Science: April/June 2020 - Volume 43 - Issue 2 - p 159-171 doi: 10.1097/ANS.0000000000000312 Buy Metrics Abstract A qualitative metasynthesis following Sandelowski and Barroso's method was conducted to explore what characterizes the existential experiences of individuals living with end-stage renal disease. The findings show that patients with end-stage renal disease live with several existential contradictions characterized by the following: perception of the body—oscillating between connection and separation, maintaining life—oscillating between freedom and captivity, uncertainty—oscillating between hope and despair, and enduring technology—oscillating between being perceived as an object and subject. Consequently, living with end-stage renal disease is challenging for patients; hence, the support of nurses is important to alleviate patients' vulnerability. © 2020 Wolters Kluwer Health, Inc. All rights reserved.