Original articlesA New Perspective on Spiritual Care Collaborative Chaplaincy and Nursing PracticeDonesky, DorAnne PhD, ANP-BC, ACHPN; Sprague, Emily BSN, RN; Joseph, Denah MS, MFT, BCCAuthor Information Touro University of California, Vallejo (Dr Donesky); Marquette University, Milwaukee, Wisconsin (Ms Sprague); and University of California, San Francisco (Ms Joseph). Correspondence: DorAnne Donesky, PhD, ANP-BC, ACHPN, Touro University of California, 1091 Azuar Dr, Vallejo, CA 94592 (firstname.lastname@example.org). Dr Donesky received funding from Josiah Macy Jr Foundation and from the Cambia Foundation that supported her salary during the preparation of this article. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Advances in Nursing Science: April/June 2020 - Volume 43 - Issue 2 - p 147-158 doi: 10.1097/ANS.0000000000000298 Buy Metrics Abstract Spirituality is a key focus and ethical obligation of nursing practice, but many nurses express uncertainty or discomfort with this aspect of their role. The purpose of this article is to explore the domains of religion, spirituality, and culture as commonly conceptualized by chaplains, as a framework for nurses to provide spiritual care interventions to patients in acute care hospitals. Using anecdotes and illustrations from palliative care practice, this article discusses the enhanced benefits to patients and families when spiritual needs are addressed, with specialty-level chaplain interventions, primary spiritual interventions provided uniquely by nurses, or interventions that require the cooperation of both professions. Lessons learned from the inpatient palliative care team experience can also apply to chaplaincy and nursing care for patients in settings beyond the acute care hospital and in disciplines beyond palliative care. © 2020 Wolters Kluwer Health, Inc. All rights reserved.