Original ArticlesAnalysis and Evaluation of Conceptual Model for Health-Related Quality of Life Employing Fawcett and DeSanto-Madeya's Critique FrameworkJang, Min Kyeong PhD, KOAPN, RN; Vincent, Catherine PhD, RNAuthor Information Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, University of Illinois Cancer Center (Dr Jang); and Department of Women, Children and Family Health Science, College of Nursing, University of Illinois at Chicago (Dr Vincent). Correspondence: Min Kyeong Jang, PhD, KOAPN, RN, Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, 845 S. Damen Ave, MC 802, Chicago, IL 60612 (email@example.com). The authors are grateful to Dr Carol Ferrans of the University of Illinois at Chicago for making herself available to answer questions about her Conceptual Model for Health-Related Quality of Life. This study was funded in part by the National Institute of Nursing Research of the National Institutes of Health (K24NR015340), the Sigma Alpha Lambda Chapter, and the PhD Research Award from the University of Illinois at Chicago, College of Nursing. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Advances in Nursing Science: October/December 2019 - Volume 42 - Issue 4 - p 325-340 doi: 10.1097/ANS.0000000000000273 Buy Metrics Abstract Health-related quality of life is increasingly used as a predictor in nursing research and practice because its multidimensional constructs encompass the holistic spectrum of care. This article comprehensively analyzes and evaluates the conceptual model of health-related quality of life of Ferrans and colleagues using Fawcett and Desanto-Madeya's 2013 framework. The model encompasses all relevant concepts and propositions in its theoretical foundation while maintaining consistency with the nursing metaparadigm. Also, the model has comprehensive content, appropriate context, and social and theoretical significance. To maximize the model's empirical and pragmatic adequacy, researchers should carefully define the variables associated with each concept. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.