Original ArticlesThe Health Change Trajectory Model An Integrated Model of Health ChangeChristensen, Deborah BSN, RNAuthor Information Loyola University Chicago, Chicago, Illinois. Correspondence: Deborah Christensen, BSN, RN, 1155 W. Bloomington Dr. S. #5, St. George, UT 84790 (firstname.lastname@example.org). This work is supported by 125362-GSCNP-13-348-01-SCN from the American Cancer Society. Special thanks to Nola J. Pender, PhD, for her encouragement and confidence that this work had potential and merit to the nursing community. It is not often that a student finds a mentor of such caliber and dedication. The author has disclosed that he (she) has no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Advances in Nursing Science: January/March 2015 - Volume 38 - Issue 1 - p 55-67 doi: 10.1097/ANS.0000000000000061 Buy Metrics Abstract Health and illness fluctuate across a person's life span, and various theories have been developed to address the unique perceptions and situations that accompany these fluctuations. An innovative model of health change resulted from a synthesis of the major concepts from 2 such theories: Mishel's uncertainty in illness theory and the Corbin and Strauss chronic illness trajectory framework. The proposed integrated model, the Health Change Trajectory Model, provides original conceptual definitions that operationalize trajectory framework in the context of changes in health. The use of a health trajectory perspective extends applications of the model to a wide range of health changes that result in uncertainty and ambiguity. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.