Original ArticlesTransitions, Decisions, and Regret Order in Chaos After a Cancer DiagnosisDrevdahl, Denise J. PhD, RN; Dorcy, Kathleen Shannon PhD, RNAuthor Information University of Washington Tacoma, Tacoma (Dr Drevdahl); and Seattle Cancer Care Alliance and Fred Hutchinson Cancer Research Center, Seattle (Dr Shannon Dorcy), Washington. Correspondence: Denise J. Drevdahl, PhD, RN, University of Washington Tacoma, 1900 Commerce St, Campus Box 358421, Tacoma, WA 98402 ([email protected]). This research was supported by a grant from the National Institute of Nursing Research (NINR 1 21 R21NR00947). The authors thank the participants who graciously shared their stories of decision making relative to cancer research participation. They also thank Mary Canales for her valuable comments on earlier versions of the manuscript. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Advances in Nursing Science: July/September 2012 - Volume 35 - Issue 3 - p 222-235 doi: 10.1097/ANS.0b013e318261a7a7 Buy Metrics Abstract Receiving a cancer diagnosis marks a life transition that evokes feelings of chaos. Additional transitions occur when patients with relapsed cancer must decide to pursue conventional care or participate in experimental clinical trials. Individuals with hematologic malignancies (n = 25) and their caregivers (n = 20) were interviewed about their decisions to have an experimental stem cell transplant. Noting that they had “no other choice,” participants expressed no regret posttransplant. “Doing something” perhaps helped address the chaos of cancer. This aggressive response to advanced cancer also represented a social imperative that negated the options of living with the cancer or entering palliative care. Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.