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Predicting Immune Status in Women From PTSD and Childhood and Adult Violence

Woods, Stephanie J. PhD, RN; Wineman, N. Margaret PhD, RN; Page, Gayle G. DNSc, RN, FAAN; Hall, Rosalie J. PhD; Alexander, Thomas S. PhD; Campbell, Jacquelyn C. PhD, RN, FAAN

Original Article

This study uses a predictive exploratory design to test the relationships between and among childhood maltreatment, intimate partner violence (IPV), posttraumatic stress disorder (PTSD) symptoms, and immune status in abused women. A convenience sample of 126 abused women and 12 nonabused women matched for age and race/ethnicity were recruited. The woman's current smoking habit, history of childhood maltreatment, experience of IPV, and PTSD symptoms predicted immune status. This prediction occurs through both direct and indirect pathways from IPV to immune status and from IPV to immune status through PTSD.

University of Akron College of Nursing, Akron, Ohio (Drs Woods and Wineman); the Johns Hopkins University School of Nursing, Baltimore, Md (Drs Page and Campbell); the University of Akron Department of Psychology, Akron, Ohio (Dr Hall); and Summa Health System, Akron, Ohio (Dr Alexander).

Corresponding author: Stephanie J. Woods, PhD, RN, The University of Akron College of Nursing, 209 Carroll Hall, Akron, OH 44325 (e-mail:

This research was supported by the National Institute for Nursing Research grant, 5 K23 NR007761.

© 2005 Lippincott Williams & Wilkins, Inc.