Nursing EthicsHuman Biological Materials in Research: Ethical Issues and the Role of Stewardship in Minimizing Research RisksJeffers, Brenda Recchia PhD, RNAuthor Information Associate Professor; Mennonite College of Nursing; Illinois State University; Normal, Illinois I thank Mary Cipriano Silva, PhD, RN, FAAN, for her mentorship in the development of this article as part of the Sigma Theta Tau International Distinguished Writer Program; and Gladys White, PhD, RN, Director of the ANA Center for Ethics and Human Rights, for encouraging my interest in this important area of nursing. Advances in Nursing Science: December 2001 - Volume 24 - Issue 2 - p 32-46 Buy SDC Abstract Recent scientific and technologic advances generated from the human genome project have increased the ability of researchers to study human biological materials. This has enhanced the ease with which highly personal information such as genetic makeup can be revealed about individuals, families, and communities. In addition, a change in the societal value of human biological tissue from waste to commercial resource has occurred. A new model of stewardship is developed that can be used as a guide for protecting human research participants who are involved in studies that include collecting and handling human biological samples. Nursing implications to ensure protection of human research participants are discussed. © 2001 Aspen Publishers, Inc.