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Screening for Mood Disorder in Pregnant Substance-dependent Patients

Chisolm, Margaret S. MD* †; Tuten, Michelle MSW* †; Strain, Eric C. MD* †; Jones, Hendrée E. PhD* †

Addictive Disorders & Their Treatment: June 2009 - Volume 8 - Issue 2 - p 88-98
doi: 10.1097/ADT.0b013e31817c331b
Original Articles

The Addiction Severity Index (ASI) and Beck Depression Inventory (BDI) were compared as screening tests for current mood disorder in pregnant substance-dependent patients (N=187). Mean ASI psychiatric Interviewer Severity Rating (ISR) and BDI scores for Diagnostic and Statistical Manual of Mental Disorder-IV diagnosed current mood disorder patients (n=51) were 4.4 and 17.1, respectively, and for those without current mood disorder (n=136) were 2.7 and 14.0, respectively. Areas under receiver operating characteristic curves were 0.73 (ASI) and 0.59 (BDI). The ASI psychiatric ISR predicted mood disorder with better sensitivity and specificity versus the BDI (0.82 and 0.49 for scores ≥4 vs. 0.49 and 0.62 for scores ≥17, respectively).

*Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine

The Center for Addiction and Pregnancy, Johns Hopkins Bayview Medical Center, Baltimore, MD

Supported by NIDA grants DA00332, DA12403 and DA023186.

Reprints: Dr Margaret S. Chisolm, MD, Johns Hopkins Bayview Medical Center, 5300 Alpha Commons Drive, Alpha Commons Building, 4th floor, Baltimore, MD 21224 (e-mail:

Portions of these data were presented at the 2007 College on Problems of Drug Dependence scientific meeting.

© 2009 Lippincott Williams & Wilkins, Inc.