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Substance-Induced Anxiety Disorder In Opioid Dependents

Ahmadi, Mojtaba MD; Ahmadi, Jamshid MD

Addictive Disorders & Their Treatment: December 2005 - Volume 4 - Issue 4 - p 157-159
doi: 10.1097/01.adt.0000163699.83614.25
Original Article

This study was to evaluate the rate of current substance-induced anxiety disorder in opioid dependents. It was designed to determine the prevalence of DSM-IV-based substance-induced anxiety disorder, generalized anxiety disorder, and substance-induced depression. The settings were private and government clinics. Five hundred unpaid opioid dependents who voluntarily sought treatment participated in the study. We utilized the research version of the structured clinical interview for DSM-IV Axis I Disorders (SCID-I). The mean age of the subjects (487 men and 13 women) was 33.4 years, ranging from 16 to 67. The majority (341, 68.2%) had voluntary jobs or were self-employed, and 67 (13.4%) were unemployed. The majority (299, 59.8%) had education at the level of primary, secondary, or high school, and only 19 (3.8%) were illiterate. Of the subjects, 105 (21%) had substance-induced anxiety disorder, 11 (2.2%) had generalized anxiety disorder, and 274 (54.8%) had substance-induced depression. Of the subjects 319 (63.8%) reported more than 5 years use of opioid. Of the patients, only 16 (3.2%) reported no episode of abstinence, and the majority (484, 96.8%) reported one or more episodes of abstinence. About 4.2% (21) reported less than 1 g per day, and the majority (86.4%, 432) reported between 1 to 5 g per day current use of opioids.

From the Shiraz University of Medical Sciences, Shiraz, Iran.

Reprints: Mojtaba Ahmadi, MD, P.O. Box 71345-1416, Shiraz University of Medical Sciences, Shiraz, Iran (e-mail:

© 2005 Lippincott Williams & Wilkins, Inc.