Review ArticleTowards Best Practices in the Treatment of Women With Addictive DisordersZilberman, Monica L. MD, PhD*; Tavares, Hermano MD, PhD*; Blume, Sheila B. MD†; el-Guebaly, Nady MD‡Author Information From *the Addiction Centre and ‡the Substance Abuse Division, University of Calgary, Calgary, Alberta, Canada, and †the State University of New York at Stony Brook, New York. Supported by CNPq-Brazil (Drs. Zilberman and Tavares). Address reprint requests to Monica L. Zilberman, MD, PhD, Addiction Center, Foothills Medical Center, University of Calgary, 1403-29th Street NW, Calgary, Alberta, Canada T2N 2T9. Addictive Disorders & Their Treatment: June 2002 - Volume 1 - Issue 2 - p 39-46 Buy Abstract The study of addiction in women has been given increasing recent attention. Documented gender differences in a variety of domains, including substance craving, have prevention and treatment implications. This article reviews gender differences and sex-specific effects of addiction as they relate to treatment guidelines for women with substance-related disorders. Gender differences in the following domains are summarized: screening, physiological effects of substances, medical consequences, psychiatric comorbidity, craving, and family and developmental issues. Implications for future research and best practices are discussed, with the goal of improving women's mental health throughout the life cycle. © 2002 Lippincott Williams & Wilkins, Inc.