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F-59 Free Communication/Poster - Ergogenic Aids V Friday, June 2, 2017, 1: 00 PM - 6: 00 PM Room: Hall F

Hydrogen-rich Water Modulates Redox Status Repeated Three Consecutive Days Of Strenuous Exercise.

3298 Board #203 June 2 3

30 PM - 5

00 PM

Shibayama, Yudai; Takeuchi, Kaito; Dobashi, Shohei; Koyama, Katsuhiro

Author Information
Medicine & Science in Sports & Exercise: May 2017 - Volume 49 - Issue 5S - p 941
doi: 10.1249/01.mss.0000519562.97355.a8
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PURPOSE: Repeated sprint exercise breaks redox balance, leading to cause oxidative stress. Excessive oxidative stress is considered as detrimental and thus as a likely cause of cell damage associated with severe exercise. In contrast, there is a growing evidence that the molecular hydrogen reacts with harmful oxidants such as hydroxyl radical in cells, and is proposed its potential for preventive and therapeutic applications. Therefore, we hypothesized that hydrogen-dissolved water drinking might attenuate accumulative fatigue imposed by intensive exercise for 3 consecutive days, by inhibiting excessive oxidative stress generation. To test this, we investigated the effects of hydrogen-rich water on oxidative stress induced by maximal pedaling exercises for three straight days.

METHOD: Eight male volunteers participated in this single blind, crossover, randomized controlled study. They completed two 3-day consecutive cycling exercise tests under the two conditions (i.e., hydrogen-rich and placebo water). The cycling exercise test was two 6-min sprint cycling consisted of 3 repetition of 10-s maximal effort against a resistance of 7.5 % body mass and 110-s active rest (no load pedaling). Before the first exercise test, and after the second exercise test, subjects drunk the 500 ml of hydrogen-rich (5.14 ± 0.03 ppm) or placebo water. Seven hours before exercise tests on day 1 as a baseline, and 17 hours after exercise each day, blood sample was obtained to analyze the BAP/d-ROMs as an index of oxidative status.

RESULTS: The cycling performance in both conditions were not significantly changed over three consecutive days. In placebo trial, the relative changes in BAP/d-ROMs from baseline level gradually decreased, as the day passed (Day 1 and Day 2 vs. Day 3, P<0.05, respectively). However, the hydrogen-rich water drinking suppressed the reduction in BAP/d-ROMs. DISCUSSION: Our present findings suggest that hydrogen-rich water drinking might contribute to maintain the redox status during consecutive days of strenuous exercise. This indicates that molecular hydrogen might have a potential to reduce exercise-induced oxidative damage.

© 2017 American College of Sports Medicine