F-66 Free Communication/Poster - Musculoskeletal/Neuromuscular Friday, May 31, 2019, 1: 00 PM - 6: 00 PM Room: CC-Hall WA2
The Synergic Impact of Sarcopenia and Dynapenia on Depressive Symptoms in Korean Older Adults
PURPOSE: To examine the synergistic impact of low appendicular skeletal muscle mass (ASM) and low muscle function (MF) on the risk of depressive symptoms in community-dwellers of Korean older adults.
METHODS: Data obtained from a total of 446 participants aged 65 years or older (80% women) recruited from local communities were used in this analysis. ASM and MF were assessed with dual-energy X-ray absorptiometry (DEXA) and a 30-s chair stand test, respectively. Depressive symptoms were assessed with the center for epidemiologic studies depression Scale (CES-D). Logistic regression was used to estimate odds-ratios (ORs) and 95% confidence interval (CIs) for having depressive symptoms according to ASM and MF levels. Statistical significance was tested at p=0.05.
RESULTS: The overall prevalence of depressive symptoms in this study population was approximately 16.4%, with 3.6 % of men and 12.8% women. With respect to depressive symptoms, individuals with low ASM alone or low MF alone had significantly higher ORs of 2.963 (95% CI=1.318-6.538, p=0.019) or 3.843 (95% CI=1.679-8.797, p=0.002), respectively, compared to individuals with normal ASM and MF (OR=1). In addition, individuals with low ASM and MF had a significantly higher risk of OR=7.907 (95% CI=3.354-18.640, p<0.001) compared to individuals with normal ASM and MF (OR=1).
CONCLUSION: The current findings suggest that both sarcopenia and dynapenia are independently and addictively associated with an increased risk of depressive symptoms in elderly Korean adults, implying an urgency of an intervention targeting at both muscle mass and function for a healthy aging.
This study was supported by the National Research Foundation funded by the Korean Government (NRF-2018R1D1A1B07048210 and NRF-2017R1A2B4007357).