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Telomere Length Of Middle-aged Sprinters And Endurance Runners: Relationships To Performance And Body Composition682 May 30 500 PM - 515 PM

SIMÕES, HERBERT, G.; SOUSA, CAIO, V.; DEUS, LYSLEINE, A.; AGUIAR, SAMUEL, S.; SANTOS, PATRICK, A.; BASBOSA, LUCAS, P.; SOUSA, HIGOR, G.; ROSA, ÉRICA, C.; ANDRADE, ROSÂNGELA, V.; ROSA, THIAGO, S.

Medicine & Science in Sports & Exercise: May 2018 - Volume 50 - Issue 5S - p 147
doi: 10.1249/01.mss.0000535570.03986.b4
B-41 Free Communication/Slide - Body Composition Wednesday, May 30, 2018, 3:15 PM - 5:15 PM Room: CC-Mezzanine M100D
Free

UNIVERSIDADE CATÓLICA DE BRASÍLIA, BRASÍLIA, Brazil.

(No relevant relationships reported)

PURPOSE: The telomere length (TL) of middle aged master runners (RUN) (n = 23, 52.3 ± 8.6 yrs; 12 sprinters, SPT; 11 endurance runners, END) was compared to untrained controls (CON, n = 10; 43.7 ± 9.4 yrs), and the relationships between TL to both master athletes’ performance and body composition were analyzed.

METHODS: Participants had blood samples collected for biomolecular measures. Relative leucocyte telomere length (T/S) was measured through qPCR. ANOVA and unpaired t-tests were applied to compare TL between studied groups, and the Pearson’s moment correlation was applied to verify relationships.

RESULTS: The TL of all RUN (T/S = 1.24 ± 0.73) differ from CON (T/S = 0.515 ± 0.62) (p < 0.01), while the TL of SPT (T/S = 1.495 ± 0.85) trended to be longer than END (T/S = 0.954 ± 0.46) (p = 0.076) with a large effect size (d = 0.72). It was observed a significant correlation between TL and actual performance level as percentage of the current world record for RUN (r = 0.47, p < 0.01), and a negative correlation between TL and body fat for the entire sample (r = -0.447; p < 0.01). Furthermore, a negative correlation between TL and performance decline per decade was observed for the SPT (r = -0.651, p < 0.01).

CONCLUSIONS: In conclusion, TL of studied master athletes was longer than their untrained peers, and seems to be not only a marker of health status, but also an indicator of sports longevity since both actual performance level, its decrease over years, and body composition were related to TL of studied sample.

© 2018 American College of Sports Medicine