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B-41 Thematic Poster - Macronutrient Metabolism in Athletes Wednesday, May 31, 2017, 3: 15 PM - 5: 15 PM Room: 304

Metabolic Effects of Acute Blood Flow Restricted Exercise

Glucose & Insulin

744 Board #6 May 31 3

15 PM - 5

15 PM

Osborne, Larry A.1; Harrison, Lucas1; Chen, Ge1; Pitcairn, Samuel1; Kushnick, Michael1; Hotta, Norio2

Author Information
Medicine & Science in Sports & Exercise: May 2017 - Volume 49 - Issue 5S - p 189-190
doi: 10.1249/01.mss.0000517354.82979.65
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Blood flow restricted exercise (BFRE) has gained a lot of attention as of late due to its ability to increase muscle mass and strength during low intensity exercise. BFRE results in ischemia, which has been shown to cause a shift to a greater reliance on glucose metabolism. Although the metabolic effect of traditional exercise is well studied, there is a lack of research on the metabolic effects of BFRE.

PURPOSE: Investigate the blood glucose and insulin response to a single bout of blood flow restricted exercise 12, 36, and 48 hours after completion.

METHODS: 8 healthy men (22±2 yrs), of above average VO2 max (46.2±13.4 ml/kg/min), and average body fat percentage (17.4±3.2) performed two separate trials of treadmill walking (CON & BFRE) at 50±5% of their predetermined VO2 max until 200 kcals were expended. For the BFRE trial, pressure cuffs were applied to the most proximal portion of the thigh and inflated to 200 mmHg. Subjects walked in 10-minute increments, interspersed with 2 minutes of passive recovery where the pressure cuffs were deflated. Blood samples were taken at baseline, immediately after exercise, 12 hours, 36 hours, and 48 hours post exercise bout. All values were reported in standard±mean deviation. A 2x3 Repeated Measures ANOVA, a One-way ANOVA, and a Tukey’s HSD post hoc test were utilized to evaluate differences from pre to post.

RESULTS: Minimal differences were found in the glycemic response post exercise between BFRE and CON (95.6±2.8, 99.9±14.1, 102.6±14.8, 104.6±8.2, and 96.8±4.8) vs (97.0±3.9, 93.1±8.1, 96.2±6.5, 92.8±6.2, 93.7±4.7). However, BFRE resulted in significantly lower insulin levels than CON at immediately, 12, 36, and 60 hours post exercise (18.4±7.3, 12.1±6.9, 12.2±7.8, 11.8±5.8, and 12.7±6.0) vs (17.6±7.9, 18.3±8.4, 16.5±8.7, 15.8±6.9, and 18.5±9.4).

CONCLUSION: In this small sample of apparently healthy above average aerobic fitness and average body fat men, treadmill walking to expend 200 kcals in conjunction with BFRE resulted in significant less insulin needed to elicit the same glycemic response post exercise than CON.

Research was funded in part by Sigma Xi Grant in Aide, Provosts Undergraduate Research Fund, and the College of Health Sciences and Professions Student Research Award.

© 2017 American College of Sports Medicine