Lower Choline Intake is Associated with Diminished Strength and Lean Mass Gains in Older Adults: 1154 Board #333 May 31 2: 00 PM - 3: 30 PM : Medicine & Science in Sports & Exercise

Journal Logo

B-77 Free Communication/Poster - Nutrition and Health Wednesday, May 31, 2017, 1: 00 PM - 6: 00 PM Room: Hall F

Lower Choline Intake is Associated with Diminished Strength and Lean Mass Gains in Older Adults

1154 Board #333 May 31 2

00 PM - 3

30 PM

Lee, Chang Woock1; Galvan, Elfego2; Lee, Teak V.3; Chen, Vincent CW4; Bui, Steve5; Crouse, Stephen F. FACSM4; Fluckey, James D.4; Smith, Stephen B.4; Riechman, Steven E. FACSM4

Author Information
Medicine & Science in Sports & Exercise 49(5S):p 321, May 2017. | DOI: 10.1249/01.mss.0000517748.88964.59
  • Free

PURPOSE: Choline is an essential micronutrient involved in many physiological processes including membrane integrity/signaling, lipid transport, methylation reactions, neurotransmission, and muscle contraction. We examined the relationship between habitual, food-based choline consumption and muscle responses to resistance exercise training (RET).

METHODS: Forty-six, 60-69-year-old men and women underwent 12 weeks of whole body RET (3x/week, 3 sets, 8-12 reps, 75% of maximum strength [1RM]). Body composition (DEXA) and 1RM tests were performed before and after training. After analyzing 1,656 dietary logs (3x/week for 12 weeks with 46 participants), participants’ mean choline intakes were categorized into three groups: Low (2.9-5.5 mg/kg lean/d), Med-Low (5.6-8.0 mg/kg lean/d), or Adequate (8.1-10.6 mg/kg lean/d). This corresponds to <50%, ~63%, and ~85% of Adequate Intake (AI), respectively. ANOVA/ANCOVA were performed to compare changes in composite strength (leg press + chest press 1RM) and lean mass between groups controlling for the effects of other nutrients.

RESULTS: Gains in composite strength were significantly less in the Low group compared with the other groups (Low: 30.9 ± 15.1%, Med-Low: 70.3 ± 48.5%, Adequate: 81.9 ± 68.4%; p=0.004). ANCOVA with cholesterol, protein, or other nutrients did not alter this result. Reduced gains in lean mass were also observed in the Low group, compared with the higher choline intake of 5.6-10.6 mg/kg lean/d (1.3 ± 0.6% vs. 3.2 ± 0.6%, p<0.05) with folate as a covariate.

CONCLUSION: These data suggest lower choline intake is negatively and independently associated with muscle responses to RET in older adults.

© 2017 American College of Sports Medicine