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B-76 Free Communication/Poster - Medical Issues Wednesday, May 31, 2017, 1: 00 PM - 6: 00 PM Room: Hall F

L-glutamine Enhances Plasma Glutamine And Maintains Concentrations Of Alanine And Arginine Following High Intensity Cycling

1146 Board #325 May 31 3

30 PM - 5

00 PM

Clayton, Zachary S.1; Hozman, Ari2; Braden, Brittany2; Kern, Mark2

Author Information
Medicine & Science in Sports & Exercise: May 2017 - Volume 49 - Issue 5S - p 318
doi: 10.1249/01.mss.0000517740.50846.63
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Glutamine is a naturally occurring nonessential, gluconeogenic amino acid. Prolonged exercise is associated with a decrease in intramuscular and plasma concentrations of glutamine, which may be linked to performance decrements. Thus, we hypothesized that exogenous glutamine supplementation would preserve the plasma glutamine pool following high intensity cycling, as well as improve performance in a repeated bout of cycling. Two solutions [61 g glucose polymer (PLC); 61 g glucose polymer and 0.3 g-kg-1-bodyweight L-glutamine (GLN)] were tested using a double-blind, randomized, cross-over design. During each trial, ten cyclists ingested one liter of test solution immediately following an initial exercise bout (30 min at 70% VO2 max, 6 x 1 min sprints at 140% VO2 max, 45 min at 70% VO2max) and recovered for two hours in a seated position. Immediately following the recovery period, subjects completed a time to exhaustion (cycle at 80% VO2 max until no longer maintaining 100 RPM) test. Blood was collected immediately following the initial exercise bout, after 2 h recovery, and immediately following the time to exhaustion test. Glutamine concentration was increased (p < 0.05) by approximately twofold (676±126 to 1410±636 μmol/L) from baseline to the completion of recovery for GLN, while no difference was detected in the PLC trial. At the end of recovery, GLN maintained alanine and arginine concentrations, while these amino acids significantly decreased in the PLC trial. However, the increased concentration of plasma glutamine and maintained concentrations of alanine and arginine did not influence performance (GLN: 20.98±10.35; PLC: 21.5±8.53 min).

© 2017 American College of Sports Medicine