There is inconsistent evidence regarding the association between lean body mass, fat mass, and bone mineral density (BMD) between sexes and across various populations. This inconsistency in scientific evidence on these variables presents challenges when applying current evidence on lean body mass, and BMD in clinical scenarios.
PURPOSE: The purpose of this study was to further determine the impact of fat mass, lean mass on BMD in both men and women.
METHODS: Sixty participants (males: n=24, age: 30.5±14.8; females: n=36, age: 26.3±14.8) participated in the study. Investigators examined BMD and body composition measurements using dual-energy X-ray absorptiometry (DXA).
RESULTS: Overall, BMD and lean mass were positively correlated (p < 0.01, r2=0.6). When comparing groups, a statistically significant correlation between lean mass and BMD (p < 0.05, r2=0.4) was found in women, but not in men. There were no significant correlations found between fat mass and BMD for the total sample or by sex.
CONCLUSIONS: Higher lean mass is positively associated with greater bone mineral density in women. Future investigations should examine the correlation of fat mass, lean mass distribution and BMD at different sites within the skeletal system.