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A-33 Free Communication/Poster - Aging Wednesday, May 27, 2015, 7: 30 AM - 12: 30 PM Room: Exhibit Hall F

Testosterone In Older Men

Effect Of Exercise

159 Board #10 May 27, 9

30 AM - 11

00 AM

Hayes, Lawrence D.; Sculthorpe, Nicholas; Herbert, Peter; Baker, Julien S.; Reed, Dewi; Kilduff, Liam P.; Grace, Fergal M.

Author Information
Medicine & Science in Sports & Exercise: May 2015 - Volume 47 - Issue 5S - p 26
doi: 10.1249/01.mss.0000476465.62871.19
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Advancing age in men is associated with a progressive decline in serum testosterone (T) and interactions between exercise, aging, and androgen status are only partially understood.

PURPOSE: The primary aim of this study was to establish the influence of lifelong training history on serum T, cortisol (C), and sex hormone binding globulin (SHBG) in aging men.

METHODS: Serum T, C, and SHBG were determined by radioimmunoassay (RIA) and compared between two distinct groups consisting lifelong exercising males (LE [n=20], 60.4 ± 4.7 yr) and age matched lifelong sedentary individuals (SED [n=28], 62.5 ± 5.3 years).

RESULTS: T-test revealed a lack of significant differences for serum C or SHBG between LE and SED, whilst Mann-Whitney U revealed no difference in total T, bioavailable T, or free T. ANOVA revealed significant exercise induced increases in aerobic capacity, serum T and serum SHBG (each p<0.05) but not free T or bioavailable T in the SED group following the intervention.

CONCLUSION: Findings from this investigation indicate that resting levels of serum T, and calculated free and bioavailable T do not differ in aging men, irrespective of lifelong exercise history. The present study found small but significant increases in resting levels of systemic T following exercise training in SED. However this may not be available to any exert biological effect as a result of the corresponding increase in the (SHBG) protein fraction, and further supported by the lack of any impact on free T

© 2015 American College of Sports Medicine