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Subjects with Metabolic Syndrome Have Higher Chance of Ischemia - Insight from Magnetocardiography: 2421Board #29 June 3 9:00 AM - 10:30 AM

Chen, Yung-Chih; Fang, Chin-Lung

Medicine & Science in Sports & Exercise: May 2011 - Volume 43 - Issue 5 - p 654
doi: 10.1249/01.MSS.0000401813.27398.72
E-23 Free Communication/Poster - Cardiac: JUNE 3, 2011 7:30 AM - 12:30 PM: ROOM: Hall B

National Taiwan Normal University, NTNU, Taipei, Taiwan.


(No relationships reported)

PURPOSE: The purpose of this study was to examine the relationship between endurance capacity, body composition, heart rate and ischemia (measured by magnetocardiography; MCG) in male subjects diagnosed with metabolic syndrome (MS, N=30), as well as age (45∼55yr) matched healthy male subjects (CG, N=35).

METHODS: All the subjects were received 6-minute walking, and the % body fat and body mass index (BMI) and MCG measurements. The MCG was analyzed by a receiver operating characteristic curve (ROC Curve).

RESULTS: Significantly (p<.05) higher body fat percentage (25.81±4.15 vs. 20.35±5.08 %), fat mass (20.17±4.74 vs. 14.31±4.96 kg), BMI (30.11±4.04 vs. 27.3±2.66 kg/m2) and lower endurance capacity (6-minute walking distance, 642.77±57.04 vs. 732.66±67.49 M) were found in MS group. Resting heart rate and R-R interval were not significantly different between two groups. MCG parameters including the corrected QT interval smooth index (SIQTc) (0.30±0.06 vs. 0.27±0.07), the maximum and minimum QTc interval difference (QTc dispersion) (96.59±14.72 vs. 86.83±15.93), but not the magnetic field gradient orientation (α-Angle), were significantly higher in MS group. Furthermore, QTc dispersion was positively correlated with body fat percentage (R= 0.42) and negatively correlated with endurance capacity (R= -0.31).

CONCLUSION: Body fat percentage and endurance capacity are correlated with MCG parameters. The SIQTc and QTc dispersion data suggest that subjects with metabolic syndrome may have a higher chance of ischemia which may be pathologically associated with reduced endurance capacity.

© 2011 American College of Sports Medicine