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F-25 Free Communication/Poster - Epidemiology - Diabetes, Obesity, Metabolism, CVD: JUNE 3, 2011 1: 00 PM - 6: 00 PM: ROOM: Hall B

Long-term Trends In Cardiorespiratory Fitness And The Incidence Of Hypertension

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Board #91 June 3 3:30 PM - 5:00 PM

Sawada, Susumu S. FACSM; Lee, I-Min FACSM; Naito, Hisashi; Okamoto, Takashi; Tsukamoto, Koji; Muto, Takashi; Higaki, Yasuki; Tanaka, Hiroaki; Blair, Steven N. FACSM

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Medicine & Science in Sports & Exercise: May 2011 - Volume 43 - Issue 5 - p 785-786
doi: 10.1249/01.MSS.0000402184.77668.29
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PURPOSE: Cardiorespiratory fitness is inversely associated with a decreased risk of hypertension. However, there is little information available on the relationship between long-term trends in cardiorespiratory fitness and the incidence of hypertension. We investigated the relationship between long-term trends in fitness and the incidence of hypertension in Japanese males.

METHODS: A cohort of 3,650 Japanese men free of hypertension completed annual health check-ups and cardiorespiratory fitness tests for estimated maximal oxygen uptake at least four times over seven years (1979-1985). We modeled the trend in fitness over seven years for each man using simple linear regression. Men were then divided into quartiles based on the regression coefficient (slope) from the model. During the follow-up period 1985-2004, 486 men developed hypertension. Odds ratios and 95% confidence interval (95% CI) for the incidence of hypertension were obtained using the logistic regression model.

RESULTS: Men in the lowest quartile of the distribution decreased in cardiorespiratory fitness over the seven years (median slope, -1.26 ml/kg/min), while men in the highest quartile increased in fitness (median slope, 1.31 ml/kg/min). Adjusting for age, initial fitness level, body mass index, cigarette smoking, alcohol intake, and a family history of hypertension: and using the lowest quartile as reference, the odds ratios and 95% CI for the 2nd through 4th quartiles were 0.81 (0.60-1.09), 0.84 (0.62-1.16), and 0.58 (0.41-0.82), respectively (P = 0.006 for trend).

CONCLUSIONS: These findings suggest that long-term trends in cardiorespiratory fitness is a predictor of the incidence of hypertension in Japanese males.

© 2011 American College of Sports Medicine