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B-28 Free Communication/Poster - Exercise Immunology I: JUNE 1, 2011 1: 00 PM - 6: 00 PM: ROOM: Hall B

Effects of Menstrual Cycle on the Immune Response to Basketball Training

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Board #53 June 1 2:00 PM - 3:30 PM

Yasuda, Nobuo; Ruby, Brent C. FACSM

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Medicine & Science in Sports & Exercise: May 2011 - Volume 43 - Issue 5 - p 334
doi: 10.1249/01.MSS.0000400920.74065.f8
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Determining how the menstrual cycle phase affects various aspects of immune responses is necessary to provide a comprehensive understanding of human responses to physically stressful events in women.

PURPOSE: The purpose of this study was to determine the effects of menstrual cycle on the levels of salivary Immunogloburin A (IgA) and α-amylase in female basketball players.

METHODS: Nine eumenorrhoeic female basketball players who were nationally ranked (height: 165.8±5.2 cm; body mass: 59.4±5.5 kg; body fat: 19.2±2.8 %; BMI: 21.2±1.3 kg/m2) served as the subjects. Basketball training consisted of routine ball handling, shooting and other specialized drills. Unstimulated saliva samples were collected within 10 minutes before and after (Pre and Post) basketball training sessions during the follicular (F: 6∼10 days after the onset of the menses) and luteal (L: 5∼9 days before the menses) phase for analysis of IgA concentration and α-amylase activity. Each training session lasted 3 hours.

RESULTS: With regard to the salivary α-amylase activity (kIU/L), two-way analysis of variance (ANOVA) revealed a significant main effect for time (Pre=33.6±32.0, Post=78.4±78.7 for F; Pre=43.0±28.1, Post=110.6±52.3 for L, p<0.01) before and after the basketball training session, but no difference across phase. In contrast, ANOVA for salivary IgA concentration (mg/dL) demonstrated a main effect for phase (Pre=6.9±3.1, Post=8.2±4.7 for F; Pre=10.2±3.8, Post=12.5±2.7 for L, p<0.01). However, no differences across time were apparent. Pearson's product-moment correlation showed no relationship between IgA concentration and α-amylase activity between the phases of the cycle.

CONCLUSIONS: These findings indicate that ovarian hormone concentrations in the menstrual cycle phase may influence immune parameters such as salivary IgA concentration independent of α-amylase activity reflecting sympathetic activation.

© 2011 American College of Sports Medicine