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The Local Cardiac Renin-Angiotensin-Aldosterone System

Medicine & Science in Sports & Exercise: December 2010 - Volume 42 - Issue 12 - p 2304
doi: 10.1249/01.MSS.0000390843.63822.db

ISBN: 978-1-4419-0527-7. Edition: 1st. Editors: Edward D. Frohlich, MD; Richard N. Re, MD. Specialties: Physiology, Cardiology. Publisher: Springer. List Price: $189.00

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Reporting on the proceedings of a 2008 conference, this book disseminates new findings about the local renin-angiotensin-aldosterone system (LRAAS) in the cardiovascular system and the kidneys, describing how local angiotensin conversion and renin responses in various tissues are becoming better understood. Findings from two previous conferences in 2002 and 2004 were published in monograph form in 2006.

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To provide scientists, particularly those working in the field of LRAAS biology, with the latest research information.

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This book is intended for an audience with a significant scientific or medical background. Cardiovascular-, renal-, and hypertension-oriented physicians, investigators, and scientists will find this book useful. It will do little to hold the interest of the average or advanced reader whose interest is not in the area. Students who are beginning their research careers will find this to be a great interpretation of current research.

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Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is synthesized and present in many organs including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the cardiac LRAAS. The editors have compiled a summary of presentations at the 2008 conference and provided a comprehensive review. The first chapter is designed to provide context for the rest of the book, by discussing how salt and salt processing in the body is related to disease in many vital organs (i.e., salt-sensitive hypertension). Each chapter describes data with correlations to previously known data and projections of future research.

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This work is written at an appropriate level for the intended readership. However, with limited knowledge of the information from the previous conferences, I found the book difficult to follow at some points. A short summary of the previous conferences would have been useful. The references are sufficient, current, and pertinent. The editors and authors successfully disseminated the latest LRAAS research.

RATING: ★★★★

Reviewed by: David Osborne, PhD (Texas Tech University Health Sciences Center, TX)

©2010The American College of Sports Medicine