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Drug Interaction Facts 2010

Medicine & Science in Sports & Exercise: April 2010 - Volume 42 - Issue 4 - p 834
doi: 10.1249/MSS.0b013e3181cbadf7
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ISBN: 978-1-57439-309-5. Copyright: 2010. Edition: 1st. Editor: David S. Tatro, PharmD. Specialties: Pharmacy, General Medicine, Advanced Practice, Pharmacology. Publisher: Wolters Kluwer Health. List Price: $99.95


Drug Interaction Facts 2010 provides health professionals with a fast and accurate interaction screening tool, with more than 18,000 monographs. In just seconds, potential interactions can be reviewed by class, generic drug name, or trade name. Comprehensive information on drug-drug or drug-food interactions is provided in a unique and logical quick-reference format to enhance the speed and accuracy of therapeutic decision making. Drug Interaction Facts™ provides information on the onset, severity, and documentation of clinically significant pharmacologic interactions, including a review of their effects, mechanism, and management.


To provide concise drug interaction information that can be applied in clinical practice. The drug monographs contain additional practical information regarding severity and management of interactions.


Health care practitioners and students who wish to learn about drug interactions.


The book opens with a section on principles of drug interactions, which details pharmacokinetic and pharmacodynamic drug interactions; this includes tables for easy reference to drugs that are substrates, inhibitors, and inducers of P-glycoprotein and the cytochrome P450 enzymes. Drug interaction monographs are organized alphabetically by drug and grouped by drug class. Perhaps one of the most useful tools in each monograph is the rating of the significance of the interaction from 1 to 5, which is determined by the onset, severity, and documentation of the interaction. This allows health care providers to make informed decisions about potential drug interactions. Other relevant information includes the mechanisms and the effects of drug interactions, as well as how to manage each. The final section is about drugs that prolong the electrocardiographic QT interval and the effects of cigarette smoking on drug therapy, both of which are clinically relevant and important topics.


Information on drug interactions can be cumbersome, but this book is accurate and concise. It provides practical information (i.e., severity and management of interactions), which allows informed decisions to be made and risks to be assessed. References for each monograph are pertinent, sufficient, and current. Practical information can be accessed quickly and easily, making it ideal for use in clinical practice. The editorial review panel includes experts in the field. This updated text is clinically important because it takes into account the current literature on drug interactions.

RATING: ★★★★★

Reviewed by:

Melissa Ranieri, BS, PharMD

(Temple University School of Pharmacy,

Philadelphia, PA)

©2010The American College of Sports Medicine