B-28 Free Communication/Poster - Muscle Damage and Oxidative Stress: MAY 28, 2008 1:00 PM- 6:00 PM ROOM: Hall B
'Delayed Onset Muscle Soreness' (i.e.; DOMS) is the phenomenon experienced during the 24-48 hours following a bout of eccentric exercise characterized by local muscle soreness and reduced skeletal muscle strength persisting for several days.
PURPOSE: Determine the effect of chronic dietary supplementation with polyphenols from pomegranate extract (i.e.; POMxL; POM Wonderful) on maximal, voluntary skeletal muscle strength during 96 hours of recovery following eccentric damage.
METHODS: Fifteen healthy, untrained males (24.2 Â± 1.4 y, 73.2 Â± 1.7 kg, 177.5 Â± 1.2 cm) were recruited. Subjects were randomized into a placebo controlled crossover design with two treatments provided, each given over a period of nine days. During each 9-day testing period the subject consumed either twice-daily POMxL or placebo (PLA). Following four days of supplementation, subjects performed a bout of 2 sets of 20 maximal eccentric elbow flexion exercises with one arm. Maximal strength (STR) was assessed from peak isometric force recorded with a load cell. Perceived soreness (SORE) was assessed by rating soreness on a scale of 0 to10 during voluntary flexion of the injured arm. Strength and soreness were assessed pre-exercise (BASE) and 2, 24, 48, 72, and 96 hours post-exercise. Each subject performed the next testing period using the opposite arm and treatment after a 14-day washout period.
RESULTS: Two hours post-exercise STR was reduced to 71.1% Â± 2.8 and 72.1% Â± 1.9 of BASE values in POMxL and PLA groups (p=.78). STR in POMxL compared to PLA was significantly higher at 48 h (84.3% Â± 2.8 and 78.2% Â± 2.5; p=.018) and 72 hours (88.4% Â± 2.3 and 83.8% Â± 2.3; p=.023) post-exercise. Muscle soreness was similar in PLA and POMxL, peaking during the 24-48 h period post-exercise.
CONCLUSION: These results demonstrate that chronic supplementation with POMxL significantly improves recovery of isometric strength 2-3 days following damaging eccentric exercise of the elbow flexor muscles.
Funded from grant from POMS Wonderful, LLC.