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F-54A Thematic Poster - Ergogenic: MAY 30, 2008 3: 15 PM - 5: 15 PM ROOM: 205

Effect of β-Alanine Supplementation on the Acute Hormonal Response to Resistance Exercise

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Board #5 May 30 3:15 PM - 5:15 PM

Hoffman, Jay R. FACSM1; Ratamess, Nicholas A.1; Ross, Ryan1; Kang, Jie1; Magrelli, Jason1; Neese, Kate1; Faigenbaum, Avery D. FACSM1; Wise, John A.2

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Medicine & Science in Sports & Exercise: May 2008 - Volume 40 - Issue 5 - p S166
doi: 10.1249/01.mss.0000322188.20733.93
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PURPOSE: The effect of 30 days of β-alanine supplementation (4.8 g per day) on training volume and on the acute endocrine response to resistance exercise was examined in eight experienced resistance-trained men.

METHODS: A double-blind, randomized cross-over study design was used where subjects resistance-trained and supplemented over 4-week periods consuming either β-alanine (BA) or a placebo (PL). Subjects performed an acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70% of onerepetition maximum (1-RM) with 1.5 minutes of rest between sets before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (IP), 15-minutes (15P) and 30-minutes post (30P) exercise for growth hormone, testosterone and cortisol concentrations.

RESULTS: A 22% pre-to-post difference in total number of repetitions performed was seen between BA and PL conditions, and Δ mean power was greater in BA (98.4 ± 43.8 w) vs. PL (7.2 ± 29.6 w). Growth hormone concentrations were elevated from BL at IP and 15P for both groups, while cortisol concentrations were greater than BL at all time points for both BA and PL. No group differences were noted. No significant changes from BL were seen in the testosterone response to the exercise protocol in either group.

CONCLUSIONS: Results indicate that four weeks of β-alanine supplementation can significantly improve the quality of a resistance training session in experienced resistance-trained athletes. However, these performance improvements did not affect the acute endocrine response to the exercise stimulus.

©2008The American College of Sports Medicine