C-26 Free Communication/Poster - Nutritional Interventions: MAY 31, 2007 7: 30 AM 12: 30 PM ROOM: Hall E
The Effects of Acute Exercise on Pulse Wave Velocity and Postprandial Lipaemia in men
Board #54 May 31 8:00 AM 9:30 AM
It is postulated that postprandial impairments in vascular function are mediated via an oxidative stress mechanism. Although exercise positively affects postprandial vascular dysfunction, it is currently not known whether exercise reduces oxidative stress to subsequently improve postprandial vascular function.
PURPOSE: The purpose of this study was to measure Pulse Wave Velocity (PWV) and markers of postprandial oxidative stress before and after an acute bout of moderate intensity exercise.
METHODS: Eight healthy males (age 23 ± 3yrs; height 1.81 ± 0.08m; mass 83.4 ± 16.2kg; all data mean ± SD) cycled at 60% predicted HRmax or rested for 1 hour, (trials separated by a week) then consumed a high-fat breakfast (68% of energy). Brachial-Radial PWV and measures of venous blood were obtained prior to and following exercise and at 2, 4 and 6 hours post-ingestion (2-way ANOVA).
RESULTS: PWV increased from rest (6.48 ± 1.9 m/sec) at 2 (8.9 ± 1.67 m/sec) and 4 hrs (8.99 ± 1.61 m/sec) post-ingestion in the control group only (time × group interaction, p<0.05). There was also a difference between groups at the 2 hrs post-ingestion time point; 8.9 ± 1.67 vs.6.15 ± 1.53 m/sec (timex group interaction, p <0.05). Lipid hydroperoxides increased over time (pooled exercise and control data, p<0.05). Serum triacylglycerols were elevated postprandially (pooled exercise and control data, p<0.05).
CONCLUSIONS: These findings suggest that acute exercise prior to breakfast can reduce the vascular impairments associated with the ingestion of a high-fat meal. The relationship between oxidative stress and vascular function warrants further investigation.© 2007 American College of Sports Medicine