Annual Meeting Abstracts: B-42 – Free Communication/Slide: Diabetes and Metabolic Syndrome
Obesity and physical inactivity were proved to influence insulin function and associate with type II diabetes. Besides, muscle tissue is highly related to the metabolism and storage of carbohydrate. Therefore, health related physical fitness should be the important measures for the screening and prevention for type II diabetes. PURPOSE: To investigate the performance of OGTT insulin responses at the different risk level for type II diabetes, the correlation of the health related physical fitness and OGTT insulin responses, and the interaction of body fat and aerobic capacity related to insulin responses. METHODS: A cross-sectional exploratory design was used. The extracted information was included basic data, related history, physical fitness (body composition, aerobic capacity, muscle strength and endurance, and flexibility), biochemical examination, oral glucose tolerance test (OGTT) and estimated index of insulin responses (sensitivity and secretion). Forty-five subjects who had completed all examination and did not have any exclusive criteria were included in this study (thirty females and fifteen males). RESULTS: T he insulin sensitivity decline and the necessary insulin secretion increase through the increase of risk number of type II diabetes, especially when risk number was over three. Body composition has the highest correlation with insulin responses, and aerobic capacity was the next. Besides, as the obese degree increased (BMI, waist-hip ratio, or body fat percentage increased, or muscle mass percentage decreased) and aerobic capacity decreased, both insulin resistance and the necessary insulin secretion increase gradually. CONCLUSION: The OGTT and fitness testing can early detect persons at risk of type II diabetes before the clinical sign presented.