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Murase, N1; Ichimura, S1; Kitahara, A1; Nagasawa, T1; Ueda, C1; Homma, T1; Motobe, M1; Murakami, M1; Osada, T1; Hamaoka, T FACSM1; Katsumura, T1; Fukushima, H1; Ishimaru, S1

Medicine & Science in Sports & Exercise: May 2003 - Volume 35 - Issue 5 - p S236
E-14R Free Communication/Poster Rehabilitation and Chronic Disease

1Department of Preventive Medicine and Public Health and Second Department of Surgery, Tokyo Medical University, Tokyo, JAPAN

(Sponsor: Takafumi Hamaoka, FACSM)

Peripheral arterial disease (PAD) causes intermittent claudication. Some studies have shown that walking exercise was effective in improving the walking distance in patients with intermittent claudication.

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The purpose of this study was to clarify the effects of the exercise training using bicycle ergometer for patients with PAD.

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Eight patients with PAD Fontaine grade II aged 73.0 ± 6.5 (mean ± SD) performed exercise program by bicycle ergometer 3 times a week for 6 weeks. Exercise intensity was 70% of maximal load during maximal exercise test by bicycle ergometer and exercise duration of each session was 30 min in total. Maximal oxygen uptake (VO2max) was measured with expiratory gas analysis via the breath by breath method during exercise test. At the same time, muscle oxygenation level at vastus lateralis (VL) and lateral head of gastrocnemius (GC) muscles was measured by near infrared spectroscopy and recovery time (Tr) for oxy-hemogrobin/myogrobin following exercise was calculated. Maximal walking distance (MWD) was evaluated by the treadmill test at 2.4 km/hr, 12% grade.

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After 6 weeks of exercise training, VO2max improved from 14.5 ± 2.1 ml/kg/min to 16.2 ± 2.6 ml/kg/min (p < 0.05). Tr at VL was shortened from 104 ± 64 sec to 61 ± 35 sec (p = 0.054) and Tr at VL was shortened from 91 ± 25 sec to 61 ± 28 sec (p < 0.05). MWD was prolonged from 121 ± 49 m to 225 ± 119 m (p < 0.05).

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Exercise training by bicycle ergometer improved walking distance by 86% patient with PAD. This improvement was a result of development of cardiorespiratory function as well as muscle perfusion in the lower limbs.

©2003The American College of Sports Medicine