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Oxidative Stress and Vascular Disease

Eskandari, Mark K. M.D., Reviewer

Section Editor(s): Berry, Michael J. Ph.D., FACSM, Reviewer

Medicine & Science in Sports & Exercise: July 2000 - Volume 32 - Issue 7 - p 1364
Book Reviews

Northwestern University Medical School

Oxidative Stress and Vascular DiseaseEditor: KEANEY, John F., Jr., M.D. (Boston University) Bibliographic Data: (ISBN: 0–7923-8678–7, Kluwer Boston, Inc., 2000) 373 pages, contributors, hard cover Audiences: Vascular Medicine Specialists, Vascular Biologists, Biomedical researchers Subjects: Vascular Surgery, Cardiology, Physiology Other Info: The book contains black-and-white illustrations.

DESCRIPTION: This is a thorough but concise review of the mechanisms of oxidative stress and how it has only recently been shown to play a critical role in a variety of vascular disease states. PURPOSE: The purpose, as outlined by the editor, is to define oxidative stress and its mechanisms and then delve into the specific interactions of oxidative stress and a host of pathologic vascular disease states both in animal studies and humans. These goals have been successfully achieved. AUDIENCE: The book is directed toward both basic scientists and clinicians with an interest in vascular biology. It is well written and at a level consistent with the anticipated audience. The editor has collected a competent group of scientists to assist in developing this book. ASSESSMENT: This is a well-written and up-to-date reference on the pathophysiology of a variety of vascular disease states of which oxidative stress may play an intimate role. SCORE: Weighted Numerical Score: 80 - ***

© 2000 Lippincott Williams & Wilkins, Inc.