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Physically Active Subjects Should Be the Control Group


Medicine & Science in Sports & Exercise: March 2006 - Volume 38 - Issue 3 - p 405-406
doi: 10.1249/01.mss.0000205117.11882.65
Invited Commentary

Health Activity Center, Departments of Biomedical Sciences and of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO

Editor's Note: In his 2005 Joseph B. Wolffe Memorial Lecture, Dr. Frank Booth, one of ACSM's most esteemed basic scientists, argued that researchers studying physical activity effects on health-related outcomes should adopt a new perspective when designing their studies. Dr. Booth's arguments were persuasive, passionate, and, merit our strong consideration. His perspective is summarized in this invited commentary.

Address for correspondence: Frank W. Booth, Ph.D., Department of Biomedical Sciences, University of Missouri-Columbia, E102 Veterinary Medical Building, 1600 East Rollins Road, Columbia, MO 65211; E-mail:

Submitted for publication November 2005.

Accepted for publication November 2005.

©2006The American College of Sports Medicine