The primary purpose of this study was to determine the effects of resistance exercise training on early diastolic myocardial velocities (E′) in an obese pediatric population.
Twenty-three obese adolescents were selected to participate in either a resistance-based training program (RT; n = 13, 12.2 ± 0.4 yr, body mass index [BMI] = 32.5 ± 1.9 kg·m−2) or a nonexercise control intervention (n = 10, 13.6 ± 0.7 yr, BMI = 30.2 ± 2.6 kg·m−2) for 8 wk. All subjects had repeated echocardiographic assessments to determine left ventricular (LV) geometry, early transmitral flow velocity (E), and E′.
LV mass and wall thicknesses did not significantly change with training or in controls. RT improved E′ (11.9 ± 0.5 to 13.3 ± 0.5 cm·s−1, P< 0.01) in the presence of a decrease in E/E′ (8.17 ± 0.39 to 7.06 ± 0.30 cm·s−1, P < 0.01), a marker of left atrial pressure. No changes were evident in the inactive control subjects.
A supervised 8-wk RT exercise program improved early diastolic tissue velocity in obese children, independent of changes in LV morphology.
1School of Sport Science, Exercise and Health, University of Western Australia, Crawley; 2Cardiac Transplant Unit, Royal Perth Hospital, Perth; 3Telethon Institute for Child Health Research, University of Western Australia, Crawley; Departments of 4Cardiology, 5Endocrinology and Diabetes, Princess Margaret Hospital, Subiaco, AUSTRALIA; 6Research Institute for Sport and Exercise Science, Liverpool John Moores University, UNITED KINDOM; and 7School of Medicine, The University of Notre Dame, Fremantle, AUSTRALIA
Address for correspondence: Louise H. Naylor, Ph.D., School of Sport Science, Exercise and Health, The University of Western Australia, M408 35 Stirling Highway, Crawley WA 6907, Australia; E-mail: firstname.lastname@example.org.
Submitted for publication April 2008.
Accepted for publication June 2008.