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Effect of oral creatine supplementation on isokinetic torque production


Medicine & Science in Sports & Exercise: May 2000 - Volume 32 - Issue 5 - p 993-996
Applied Sciences: Biodynamics

GILLIAM, J. D., C. HOHZORN, D. MARTIN, and M. H. TRIMBLE. Effect of oral creatine supplementation on isokinetic torque production. Med. Sci. Sports Exerc., Vol. 32, No. 5, pp. 993–996, 2000.

Purpose This study was conducted to examine the effect of oral creatine supplementation on the decline in peak isokinetic torque of the quadriceps muscle group during an endurance test.

Methods Twenty-three active, but untrained, male subjects performed isokinetic strength tests on a Cybex II dynamometer at 180°·s−1. The protocol consisted of pre- and post-tests with five sets of 30 maximum volitional contractions with a 1-min rest period between sets. Subjects returned to perform the posttest after 5 d of placebo (4 × 6g glucose·d−1, N = 12) or creatine (4 × 5g creatine + 1 g glucose·d−1, N = 11) supplementation. Supplements and testing were administered in a double blind fashion. Peak torque was measured during each contraction and the 30 contractions were averaged for each set.

Results A three-way mixed ANOVA with one between factor (placebo vs creatine) and two within factors (pre/post supplementation and sets 1–5) revealed no significant interactions, P > 0.05. The placebo vs creatine main effect was also nonsignificant, whereas the pre/post and set effects were significant (P < 0.05). Peak torque increased (∼ 3%) from pre- to post-testing, (P = 0.04), but the absolute magnitude of the differences is unlikely to be of any practical significance. Peak torque decreased from sets 1 to 4, whereas sets 4 and 5 were not different. A priori contrasts comparing the creatine group’s performance pre vs post test for the fourth and fifth sets were nonsignificant (P > 0.05).

Conclusions Based on within and between group comparisons, we were unable to detect an ergogenic effect of oral creatine supplementation on the decline in peak torque during isokinetic exercise at 180°·s−1.

Department of Physical Therapy, University of Florida, Gainesville, FL 32610

Submitted for publication March 1999.

Accepted for publication August 1999.

Address for correspondence: Jeffery D. Gilliam, University of Florida University of Florida, Department of Physical Therapy Department of Physical Therapy, P.O. Box 100154, Gainesville, FL 32610. E-mail:

© 2000 Lippincott Williams & Wilkins, Inc.